iBONi siRNA box
All-in-one solution for gene knockdown
3 x pre-designed iBONi siRNA
1 x iBONi siRNA negative control
1 x riboxxFECT transfection reagent
siRNA amount: 2 or 5 nmol each
Quality control: PAGE
Transfection reagent: 250 µl
In order to make gene knockdown experiments easier and more effective, Riboxx offers the iBONi siRNA box. The iBONi siRNA box is a powerful all-in-one solution with a package of perfectly matched tools for every step of gene knockdown experiments. It includes 3x pre-designed iBONi siRNAs targeting one gene, 1x iBONi siRNA negative control, and riboxxFECT transfection reagent.
iBONi siRNA displays the RNAi-cap, a new technology invented at Riboxx. The RNAi-cap technology offers several advantages:
- directional modulation of RISC unwinding of siRNA duplex, enhancing loading of the guide strand to the RISC complex. As a consequence, much less siRNA are needed for an effective gene silencing with a subsequent reduction of off-target effects 
- improved stability of siRNA duplex with subsequent improved half-life in body fluids.
 Nolte A, Ott K, Rohayem J, Walker T, Schlensak C, Wendel HP. Modification of small interfering RNAs to prevent off-target effects by the sense strand. N Biotechnol. 2013 Jan 25;30(2):159-65.
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