Karsten Tlusty

Did you know that siRNA and miRNA mimics are manufactured using solid-phase chemical synthesis?
This standard process uses highly toxic solvents such as acetonitrile, dichloromethane, and is run on synthesizers with high energy costs.
This is a very serious burden for the environment!
At Riboxx, we implement Green Chemistry for manufacturing of our siRNA and miRNA mimics.

Last week, a scientist asked me: “ I am targeting a mRNA with a miRNA mimic. It is working, but I need a stronger silencing. Can you help?"
This is a known problem when you are restricted in your target sequence, such as for miRNA mimics.
The solution to this problem is the RNAi-cap.

One of the problems of siRNA and miRNA mimic is unspecific gene silencing due to off-target effects. I have solved this problem by inventing the RNAi-cap.

You have surely someday asked yourself: "What is the purpose of being an INVENTOR?"
This short movie brings it to the point.