Scientific Publications
2010
Rohayem J, Bergmann M, Gebhardt J, Gould E, Tucker P, Mattevi A, Unge T, Hilgenfeld R, Neyts J. Antiviral strategies to control calicivirus infections. Antiviral Res. 2010 Aug; 87(2): 162-78.
2009
Rohayem J. Norovirus seasonality and the potential impact of climate change. Clin Microbiol Infect. 2009 Jun; 15(6): 524-7.
Speroni S, Rohayem J, Nenci S, Bonivento D, Robel I, Barthel J, Luzhkov VB,Coutard B, Canard B, Mattevi A. Structural and biochemical analysis of human pathogenic astrovirus serine protease at 2.0 A resolution. J Mol Biol. 2009 Apr 17;387(5):1137-52. Epub 2009 Feb 26.
Högbom M, Jäger K, Robel I, Unge T, Rohayem J. The active form of the norovirus RNA-dependent RNA polymerase is a homodimer with cooperative activity. J Gen Virol. 2009 Feb;90(Pt 2):281-91.
2008
Robel I, Gebhardt J, Mesters JR, Gorbalenya A, Coutard B, Canard B, Hilgenfeld R, Rohayem J. Functional characterization of the cleavage specificity of the sapovirus chymotrypsin-like protease. J Virol. 2008 Aug;82(16):8085-93. Epub 2008 Jun 11.
De Palma AM, Heggermont W, Lanke K, Coutard B, Bergmann M, Monforte AM, Canard B, De Clercq E, Chimirri A, Pürstinger G, Rohayem J, van Kuppeveld F, Neyts J. The thiazolobenzimidazole TBZE-029 inhibits enterovirus replication by targeting a short region immediately downstream from motif C in the nonstructural protein 2C. J Virol. 2008 May;82(10):4720-30. Epub 2008 Mar 12.
2007
Coutard B, Gorbalenya AE, Snijder EJ, Leontovich AM, Poupon A, De Lamballerie X, Charrel R, Gould EA, Gunther S, Norder H, Klempa B, Bourhy H, Rohayem J,L'hermite E, Nordlund P, Stuart DI, Owens RJ, Grimes JM, Tucker PA, Bolognesi M, Mattevi A, Coll M, Jones TA, Aqvist J, Unge T, Hilgenfeld R, Bricogne G, Neyts J, La Colla P, Puerstinger G, Gonzalez JP, Leroy E, Cambillau C, Romette JL, Canard B. The VIZIER project: preparedness against pathogenic RNA viruses. Antiviral Res. 2008 Apr;78(1):37-46. Epub 2007 Nov 29.
Scheffler U, Rudolph W, Gebhardt J, Rohayem J. Differential cleavage of the norovirus polyprotein precursor by two active forms of the viral protease. J Gen Virol. 2007 Jul;88(Pt 7):2013-8.
2006
Fullerton SW, Blaschke M, Coutard B, Gebhardt J, Gorbalenya A, Canard B,Tucker PA, Rohayem J. Structural and functional characterization of sapovirus RNA-dependent RNA polymerase. J Virol. 2007 Feb;81(4):1858-71. Epub 2006 Nov 22.
Rohayem J, Jäger K, Robel I, Scheffler U, Temme A, Rudolph W. Characterization of norovirus 3Dpol RNA-dependent RNA polymerase activity and initiation of RNA synthesis. J Gen Virol. 2006 Sep;87(Pt 9):2621-30.
Rohayem J, Robel I, Jäger K, Scheffler U, Rudolph W. Protein-primed and de novo initiation of RNA synthesis by norovirus 3Dpol. J Virol. 2006 Jul;80(14):7060-9.
2005
Rohayem J, Münch J, Rethwilm A. Evidence of recombination in the norovirus capsid gene. J Virol. 2005 Apr;79(8):4977-90.
2004
Rieger MA, Ebner R, Bell DR, Kiessling A, Rohayem J, Schmitz M, Temme A, Rieber EP, Weigle B. Identification of a novel mammary-restricted cytochrome P450, CYP4Z1, with overexpression in breast carcinoma. Cancer Res. 2004 Apr 1;64(7):2357-64.
2002
Temme A, Morgenroth A, Schmitz M, Weigle B, Rohayem J, Lindemann D, Füssel M, Ehninger G, Rieber EP. Efficient transduction and long-term retroviral expression of the melanoma-associated tumor antigen tyrosinase in CD34(+) cord blood-derived dendritic cells. Gene Ther. 2002 Nov;9(22):1551-60.
Schmitz M, Rohayem J, Paul R, Weigle B, Stein A, Rieber EP. Quantification of antigen-reactive T cells by a modified ELISPOT assay based on freshly isolated blood dendritic cells. J Clin Lab Anal. 2002;16(1):30-6.
2000
Rohayem J, Diestelkoetter P, Weigle B, Oehmichen A, Schmitz M, Mehlhorn J, Conrad K, Rieber EP. Antibody response to the tumor-associated inhibitor of apoptosis protein survivin in cancer patients. Cancer Res. 2000 Apr 1;60(7):1815-7.
1999
Rohayem J, Conrad K, Zimmermann T, Frank KH. Comparison of the diagnostic accuracy of three commercially available enzyme immunoassays for anti-p53 antibodies. Clin Chem. 1999 Nov;45(11):2014-6